Then Abraham returned to his servants, and they set off together for Beersheba. And Abraham stayed in Beersheba. Genesis 22:19
Then Rebekah and her attendants got ready and mounted the camels and went back with the man. So the servant took Rebekah and left. Now Isaac had come from Beer Lahai Roi, for he was living in the Negev. Genesis 24:61-62
Isaac brought her into the tent of his mother Sarah, and he married Rebekah. So she became his wife, and he loved her; and Isaac was comforted after his mother’s death. Genesis 24:67
After Abraham trusts God to the point of offering Isaac on the altar, God tells him to stop, and provides a ram for the sacrifice. God calls to Abraham and says that because you have done this and have not withheld your son, your only son, I will surely bless you and make your descendants as numerous as the stars in the sky and as the sand on the seashore. Then Abraham returns to his servant (v.19). It is interesting to note that the last we see of Isaac was when Abraham laid him on the altar. It is assumed Isaac returns with Abraham and the servants to their home in Beersheba, but there is no mention of it.
As a model of future events, Isaac is not seen again until Rebekah is brought to Isaac to become his bride. Years later, God’s only son Jesus is crucified and after being resurrected and returning to heaven will not be seen until He comes back for His bride, the church. Jesus is coming soon; bride be ready.